The Greek-island chain that hugs the south-west Turkish coast — twelve main islands strung from Patmos in the north to Kastellorizo in the far east, plus a handful of lesser ones. Rhodes is the headline: the largest still-inhabited medieval walled city in Europe (UNESCO since 1988), the Crusader-Knights' fortress, the white village of Lindos under its 4th-century acropolis. Symi is the neoclassical-mansion harbour overnight everyone says they'll do as a day trip and then regrets not staying. Patmos is the religious island — the Cave of the Apocalypse, the 1088 Monastery of St John, the Skala harbour the yacht crowd discovered ten years ago.
The Dodecanese is the Greek chain that looks at Turkey, not at Italy — the one where the Crusader Knights of St John ran the show for 213 years (1309–1522) before the Ottomans, where the Italians ran it again 1912–1947 (under Mussolini, who left behind a fascist-modernist administrative quarter in Rhodes Town), and where the medieval-walled cities of Rhodes Old Town and the cliff-top Acropolis of Lindos sit alongside the half-Turkish, half-Italian rooftop of Symi and the monastic UNESCO-listed Patmos. The most layered Greek chain — and the one where the "headline island" (Rhodes) genuinely earns the headline.
Fly into Rhodes (RHO) — direct routes from London and most European hubs May–October — or Kos (KGS) if you're starting north. Symi is a 50–90-min ferry from Rhodes; Patmos is reachable via Kos or by overnight ferry from Piraeus. The chain is spread across 200 km of sea, so the right shape is two islands a week, not five. The flagship trip is Rhodes (4 nights) + Symi (3); the alternative is Patmos (4) + Kos (2) + Patmos (1 more).
Rhodes for the medieval city. Symi for the harbour overnight. Patmos for the monastery.
The Dodecanese is the layered chain. Crusader, Ottoman, Italian and Greek histories on the same islands; the cooking shows it, the architecture shows it, the wine-and-coffee culture shows it. May, June, September, early October are the windows — Lindos Acropolis is climbable in the morning without collapsing in the heat, Symi's harbour rooms are open, Patmos is not yet over-yachted. July–August bring 38°C inland on Rhodes and full Lindos-bus chaos. November–April most boutique hotels close, especially on Symi and Patmos.
Rhodes is the headline; Symi is the overnight everyone misses; Patmos is the religious pilgrimage; Kos is the second-biggest but most package-y; Karpathos is the under-touristed mountain-and-windsurf alternative; Kastellorizo is the tiny easternmost dot two km from Turkey.
The chain's headline and the largest still-inhabited medieval walled city in Europe — UNESCO since 1988. The Palace of the Grand Masters, the cobbled Street of the Knights, the Archaeological Museum in the old infirmary, the Jewish Quarter. The boutique-hotel cluster inside the walls is where to base. Lindos, an hour down the east coast, is the white cliff-village under its 4th-century-BC acropolis. Three to four nights minimum.
A 50–90-min ferry north of Rhodes — and the chain's most-photographed single image. Yialos harbour is a horseshoe of pastel-painted 19th-century neoclassical mansions stacked up the hillside, with the medieval Chorio at the top of the Kali Strata (a 500-step stone staircase). Most people see Symi for two hours off a Rhodes day-boat; stay overnight instead — the town empties at 6 p.m. and turns gold.
The religious island — the Cave of the Apocalypse where John the Divine is said to have written Revelation, the Monastery of St John (founded 1088, UNESCO-listed). Chora is the hilltop village around the monastery walls; Skala is the harbour the yacht crowd discovered ten years ago. Sapsila is the quiet bay just south. Ferry from Kos or overnight from Piraeus (8 hrs). Closed hard Nov–Easter.
The second-biggest, the most package-resort, and Hippocrates's birthplace — the 4th-century-BC Asclepieion (the healing sanctuary where the Hippocratic Oath was effectively born) is 4 km outside Kos Town. The plane tree of Hippocrates on Plateia Platanou is the (likely-mythic-but-still-photographed) tree he was meant to have taught under. Base in Kos Town; skip the south-coast all-inclusive strip.
Halfway between Rhodes and Crete — long, narrow, mountainous, the chain's least-developed major island. Olympos the cliff-top traditional village (where the women still wear the regional dress at festivals); Pigadia the port-and-base; Afiartis at the south tip — one of Europe's top windsurfing beaches. The pick for travellers who want a Greek island that hasn't been styled for Instagram.
The easternmost point of Greece, a one-village island 2 km off the Turkish coast (with the Turkish town of Kaş visible across the strait). Two streets around a horseshoe harbour, a Blue Cave (Parastas) reached by boat, Lycian rock tombs in the cliff. The film Mediterraneo (1991 Oscar Best Foreign Film) was shot here. 25-min flight from Rhodes (KZS), or a weekly ferry. The Greek island for people who don't want a "Greek island."
Crusader, Ottoman and Italian centuries left a different table on these islands. Twenty-one picks across four bases — Rhodes (Old Town + Lindos), Symi, Patmos, and the Karpathos + Kastellorizo south-east. Book Mavrikos, Noble Gourmet, Benetos, Vegghera and Pleiades a few days out; book The Olive Tree as a Symi lunch walk-up. Most rooms close Nov–Easter.
Two flavours of stay across the chain: small boutiques inside the medieval walls (Kókkini Porta Rossa and Marco Polo Mansion in Rhodes Old Town; The Old Markets at the foot of Symi's Kali Strata), and a tier of beach-luxury along the Rhodes coast (Lindos Mare, Aquagrand, Atrium Prestige). Patmos is mostly small properties — Petra above Grikos is the SLH pick. Thirteen across three tiers; almost all closed Nov–Easter.
Seven rooms means a 4–5 month booking lead in summer. The Marco Polo Cafe garden serves dinner too; it's the easy stay-in night between Old-Town tavernas.
Some rooms have shared courtyard access; confirm at booking if you want private outdoor space. No pool; the Old Town is the property.
Get to Chora (the hilltop monastery village) by short cab; the property itself is harbour-side. Closes hard Nov–Easter, like most of Patmos.
Books out 6+ months ahead in season. No pool; the property is the room. Pair with Lindos Mare or Aquagrand for the second half of a Rhodes-only week if you want a beach.
Verify season — Casa Cook properties sometimes close earlier than the Rhodes-coast competition. The cab to Lindos is €40+; rent a car for the Lindos days.
The location at the bottom of the Kali Strata means you can choose Yialos-harbour life or climb the 500 steps for the Chora air. Books out 4+ months ahead in season.
The garden suites are the upgrade — the pool-side ones are good but the property's gardens are its real surprise. Walk-everywhere to Mythos and Manos Fish.
"Sea View Junior Suite" is the upgrade that justifies the rate jump. Closed hard Nov–April. Quieter than the Skala harbour properties; rent a small boat for a Patmos day-trip out of Grikos.
Confirm specific villa category at booking — the units vary in size and outdoor space. The Sapsila bay is the quieter Patmos micro-zone; Skala is a 10-min cab when you want it.
Six rooms means it books 6+ months ahead for August. No on-site restaurant; you'll water-taxi back into Yialos for dinner at Mythos or Manos Fish.
"Sea View" suites face Bodrum on the Turkish coast. The cab into Kos Town for dinner is 10 minutes; skip the package-resort strip south.
The "Premium Suite with Private Pool" tier is the upgrade that earns it. Cab to Lindos village is €15; do the village in the early morning before the day-bus crowd lands.
"Suite with Private Pool" is the booking; the standard rooms are good but the property is built around the suite tier. Walk into Lindos at sunset rather than mid-day.
The south-coast location is meaningfully more remote than the Lindos cluster — rent a car. The villa-with-pool tier is the upgrade; thalasso programme is the second.
The two properties share the bay — confirm which one has the suite category you want. Cab to Lindos village 5 minutes; book it for a 7 a.m. acropolis climb before the heat.
The Honeymoon Suites face the bay directly; standard rooms are garden-set. Closes Nov–Easter; the 2026 season opens around mid-April.
Twelve things, four categories. Rhodes Old Town and Lindos are the medieval-Crusader mornings. The Patmos Monastery is the pilgrimage. Symi's Kali Strata is the walk. Kastellorizo's Blue Cave is the half-day-boat to the eastern edge of Greece.
Four nights on Rhodes (Old Town + Lindos), three on Symi (Yialos overnight, the boat-day, the Kali Strata at sunset), back to Rhodes to fly home. The most coherent Dodecanese week for first-time travellers. The alternative "Patmos-led" week is in Worth Knowing.
Crusader, Ottoman and Italian centuries on the same islands — the table shows it. Order these and you've eaten the Dodecanese.
Six lived-in things that change the trip.
Most Rhodes-based travellers do Symi as a 6-hour day-boat tour, get fried shrimp on the harbour, leave at 3 p.m. — and miss the island. Stay overnight at The Old Markets or Iapetos Village. The Yialos harbour at 8 p.m., after the day boats have left, is the moment the trip turns golden.
Donkey rides to the acropolis are regulated as of 2024 (max 60 minutes daily per donkey, no midday work, route limits) but still operating. The kinder move — and the more rewarding one — is to walk up at 8 a.m. before the heat. €12 entry; the cobbled climb is part of the experience.
The 1088 Monastery of St John on Patmos is still a working religious site — covered shoulders, long skirts or trousers, no shorts. Shawls and wraps are available at the entrance but limited; wear long-sleeves to keep moving. The Cave of the Apocalypse below has the same rule. Open 9–13 daily.
Fly into Rhodes (RHO) for the Rhodes + Symi week — direct from London / European hubs May–October. For Patmos, fly to Athens or Kos (KGS) and ferry on (Patmos has no airport). Karpathos has its own airport (AOK) but mostly Athens domestic; Kastellorizo is 25-min flight from RHO.
Most boutique hotels on Symi, Patmos, Karpathos and Kastellorizo close November through Easter. Marco Polo Mansion is April–October; Benetos and Petra on Patmos are May–October. Rhodes Old Town hotels stay open year-round; Lindos resorts mostly close late October.
Rhodes has Faliraki on the east coast — the British-charter party strip the chain is sometimes mocked for. Kos has the all-inclusive south-coast strip around Kardamena. Stay at the opposite end of either island: on Rhodes, the Old Town or Lindos/Vlicha. On Kos, Kos Town. The Dodecanese rewards the right base.
Tell us when you're going to the Dodecanese, for how long, the kind of trip you want — the flagship Rhodes + Symi week, a Patmos-led monastery-and-Skala trip, a Karpathos-led under-touristed week, or a Kastellorizo escape. We'll send a custom itinerary in 72 hours: hotels, restaurants (Mavrikos, Benetos and Mythos booked), the right airport, the ferry-or-flight routing, the Lindos morning logistics. Unlimited revisions until it's right.
$50, one time.
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